Monday, 26 July 2010

Binafin




Binafin may be available in the countries listed below.


Ingredient matches for Binafin



Terbinafine

Terbinafine hydrochloride (a derivative of Terbinafine) is reported as an ingredient of Binafin in the following countries:


  • Russian Federation

International Drug Name Search

Saturday, 24 July 2010

Zofran ODT


See also: Generic Zofran


Zofran ODT is a brand name of ondansetron, approved by the FDA in the following formulation(s):


ZOFRAN ODT (ondansetron - tablet, orally disintegrating; oral)



  • Manufacturer: GLAXOSMITHKLINE

    Approval date: January 27, 1999

    Strength(s): 4MG [AB], 8MG [RLD][AB]

Has a generic version of Zofran ODT been approved?


A generic version of Zofran ODT has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available - possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Zofran ODT and have been approved by the FDA:


ondansetron tablet, orally disintegrating; oral



  • Manufacturer: AUROBINDO PHARMA

    Approval date: April 12, 2010

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: BARR

    Approval date: June 25, 2007

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: GLENMARK GENERICS

    Approval date: June 27, 2007

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: MYLAN

    Approval date: June 25, 2007

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: NESHER PHARMS

    Approval date: June 25, 2007

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: PAR PHARM

    Approval date: December 26, 2006

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: RANBAXY

    Approval date: February 24, 2011

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: SANDOZ

    Approval date: August 13, 2007

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: SUN PHARM INDS

    Approval date: August 2, 2007

    Strength(s): 4MG [AB], 8MG [AB]


  • Manufacturer: TEVA

    Approval date: June 25, 2007

    Strength(s): 4MG [AB], 8MG [AB]

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Zofran ODT. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Freeze-dried compositions
    Patent 5,955,488
    Issued: September 21, 1999
    Inventor(s): Winterborn; Ian Keith
    Assignee(s): Glaxo Wellcome Inc.
    The invention relates to a freeze-dried dosage form for oral administration capable of being rapidly disintegrated in the mouth comprising ondansetron in the form of its free base or a pharmaceutically acceptable solvate thereof and one or more pharmaceutically acceptable excipients. Methods for the manufacture of such compositions and for their use in the treatment of conditions mediated through the action of 5-hydroxytryptamine (5HT) at 5HT.sub.3 receptors are also described.
    Patent expiration dates:

    • November 14, 2015


    • May 14, 2016
      ✓ 
      Pediatric exclusivity




  • Ondansetron freeze-dried dosage form compositions for oral administration
    Patent 6,063,802
    Issued: May 16, 2000
    Inventor(s): Winterborn; Ian Keith
    Assignee(s): Glaxco Wellcome Inc.
    The invention relates to a freeze-dried dosage form for oral administration capable of being rapidly disintegrated in the mouth comprising ondansetron in the form of its free base or a pharmaceutically acceptable solvate thereof and one or more pharmaceutically acceptable excipients. Methods for the manufacture of such compositions and for their use in the treatment of conditions mediated through the action of 5-hydroxytryptamine (5HT) at 5HT.sub.3 receptors are also described.
    Patent expiration dates:

    • November 14, 2015


    • May 14, 2016
      ✓ 
      Pediatric exclusivity



See also...

  • Zofran ODT Orally Disintegrating Tablets Consumer Information (Wolters Kluwer)
  • Zofran ODT Consumer Information (Cerner Multum)
  • Zofran ODT Advanced Consumer Information (Micromedex)
  • Zofran ODT Oral, Oromucosal Advanced Consumer Information (Micromedex)
  • Ondansetron Consumer Information (Drugs.com)
  • Ondansetron Consumer Information (Wolters Kluwer)
  • Ondansetron Orally Disintegrating Tablets Consumer Information (Wolters Kluwer)
  • Ondansetron Soluble Film Consumer Information (Wolters Kluwer)
  • Ondansetron Solution Consumer Information (Wolters Kluwer)
  • Ondansetron Tablets Consumer Information (Wolters Kluwer)
  • Ondansetron Consumer Information (Cerner Multum)
  • Ondansetron injection Consumer Information (Cerner Multum)
  • Ondansetron Oral, Injection, Intravenous Advanced Consumer Information (Micromedex)
  • Ondansetron Oral, Oromucosal Advanced Consumer Information (Micromedex)
  • Ondansetron Hydrochloride AHFS DI Monographs (ASHP)

Wednesday, 21 July 2010

Lisinopril / Hydrochlorothiazide




Ingredient matches for Lisinopril / Hydrochlorothiazide



Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Lisinopril / Hydrochlorothiazide in the following countries:


  • United States

Lisinopril

Lisinopril is reported as an ingredient of Lisinopril / Hydrochlorothiazide in the following countries:


  • United States

International Drug Name Search

Tuesday, 20 July 2010

Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical


Generic Name: salicylic acid (Topical route)


sal-i-SIL-ik AS-id


Commonly used brand name(s)

In the U.S.


  • Akurza

  • Aliclen

  • Avosil

  • Betasal

  • Compound W

  • Corn Removing

  • Dermarest Psoriasis

  • DHS Sal

  • Drytex

  • Duofilm

  • Duoplant

  • Durasal

  • Freezone

  • Fung-O

  • Gets-It Corn/Callus Remover

  • Gordofilm

  • Hydrisalic

  • Ionil

  • Ionil Plus

  • Keralyt

  • Keralyt Scalp

  • Lupicare

  • Mediplast

  • Mg217 Sal-Acid

  • Mosco Corn & Callus Remover

  • Neutrogena

  • Occlusal-HP

  • Off-Ezy

  • Oxy Balance

  • P & S

  • Palmer's Skin Success Acne Cleanser

  • Propa pH

  • Salac

  • Sal-Acid Plaster

  • Salactic Film

  • Salex

  • Salitop

  • Salkera

  • Sal-Plant Gel

  • Salvax

  • Seba-Clear

  • Stri-Dex

  • Thera-Sal

  • Therasoft Anti-Acne

  • Tinamed

  • Ti-Seb

  • Virasal

  • Wart-Off Maximum Strength

  • Zapzyt

In Canada


  • Acnex

  • Acnomel Acne Mask

  • Clear Away Wart Removal System

  • Compound W One-Step Wart Remover

  • Compound W Plus

  • Dr. Scholl's Clear Away One Step Plantar Wart Remover

  • Dr. Scholl's Cushlin Ultra Slim Callus Removers

  • Dr. Scholl's Cushlin Ultra Slim Corn Removers

  • Duoforte 27

  • Freezone - One Step Callus Remover Pad

  • Freezone - One Step Corn Remover Pad

Available Dosage Forms:


  • Soap

  • Lotion

  • Liquid

  • Foam

  • Ointment

  • Gel/Jelly

  • Solution

  • Cream

  • Pad

  • Paste

  • Shampoo

  • Dressing

  • Stick

Therapeutic Class: Antiacne


Pharmacologic Class: NSAID


Chemical Class: Salicylate, Non-Aspirin


Uses For Dr. Scholl's Clear Away One Step Plantar Wart Remover


Salicylic acid is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.


Some of these preparations are available only with your doctor's prescription.


Before Using Dr. Scholl's Clear Away One Step Plantar Wart Remover


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.


Geriatric


Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with this medicine.


Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Abciximab

  • Argatroban

  • Bivalirudin

  • Cilostazol

  • Citalopram

  • Clovoxamine

  • Dabigatran Etexilate

  • Dipyridamole

  • Escitalopram

  • Femoxetine

  • Flesinoxan

  • Fluoxetine

  • Fluvoxamine

  • Fondaparinux

  • Heparin

  • Lepirudin

  • Nefazodone

  • Paroxetine

  • Protein C

  • Rivaroxaban

  • Sertraline

  • Sibutramine

  • Ticlopidine

  • Tirofiban

  • Vilazodone

  • Zimeldine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acenocoumarol

  • Anisindione

  • Ardeparin

  • Azilsartan Medoxomil

  • Azosemide

  • Bemetizide

  • Bendroflumethiazide

  • Benzthiazide

  • Bumetanide

  • Buthiazide

  • Candesartan Cilexetil

  • Certoparin

  • Chlorothiazide

  • Chlorthalidone

  • Clopamide

  • Cyclopenthiazide

  • Dalteparin

  • Danaparoid

  • Dicumarol

  • Enoxaparin

  • Eprosartan

  • Ethacrynic Acid

  • Furosemide

  • Hydrochlorothiazide

  • Hydroflumethiazide

  • Indapamide

  • Irbesartan

  • Losartan

  • Methyclothiazide

  • Metolazone

  • Nadroparin

  • Olmesartan Medoxomil

  • Parnaparin

  • Phenindione

  • Phenprocoumon

  • Piretanide

  • Polythiazide

  • Probenecid

  • Reviparin

  • Tamarind

  • Tasosartan

  • Telmisartan

  • Tinzaparin

  • Torsemide

  • Trichlormethiazide

  • Valsartan

  • Warfarin

  • Xipamide

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Blood vessel disease

  • Diabetes mellitus (sugar diabetes)—Use of this medicine may cause severe redness or ulceration, especially on the hands or feet

  • Inflammation, irritation, or infection of the skin—Use of this medicine may cause severe irritation if applied to inflamed, irritated, or infected area of the skin

  • Influenza (flu) or

  • Varicella (chicken pox)—This medicine should not be used in children and teenagers with the flu or chicken pox. There is a risk of Reye's syndrome.

  • Kidney disease or

  • Liver disease—Using this medicine for a long time over large areas could result in unwanted effects

Proper Use of salicylic acid

This section provides information on the proper use of a number of products that contain salicylic acid. It may not be specific to Dr. Scholl's Clear Away One Step Plantar Wart Remover. Please read with care.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of absorption through the skin and the chance of salicylic acid poisoning.


If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap) to be applied over this medicine, make sure you know how to apply it. Since an occlusive dressing will increase the amount of medicine absorbed through your skin and the possibility of salicylic acid poisoning, use it only as directed. If you have any questions about this, check with your doctor.


Keep this medicine away from the eyes and other mucous membranes, such as the mouth and inside of the nose. If you should accidentally get some in your eyes or on other mucous membranes, immediately flush them with water for 15 minutes.


To use the cream, lotion, or ointment form of salicylic acid:


  • Apply enough medicine to cover the affected area, and rub in gently.

To use the gel form of salicylic acid:


  • Before using salicylic acid gel, apply wet packs to the affected areas for at least 5 minutes. If you have any questions about this, check with your health care professional.

  • Apply enough gel to cover the affected areas, and rub in gently.

To use the pad form of salicylic acid:


  • Wipe the pad over the affected areas.

  • Do not rinse off medicine after treatment.

To use the plaster form of salicylic acid for warts, corns, or calluses:


  • This medicine comes with patient instructions. Read them carefully before using.

  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.

  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.

  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.

  • Cut the plaster to fit the wart, corn, or callus and apply.

  • For corns and calluses:
    • Repeat every 48 hours as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.

    • Corns or calluses may be soaked in warm water for 5 minutes to help in their removal.


  • For warts:
    • Depending on the product, either:
      • Apply plaster and repeat every 48 hours as needed, or
        • Apply plaster at bedtime, leave in place for at least 8 hours, remove plaster in the morning, and repeat every 24 hours as needed.



    • Repeat for up to 12 weeks as needed, or as directed by your doctor, until wart is removed.


  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

To use the shampoo form of salicylic acid:


  • Before applying this medicine, wet the hair and scalp with lukewarm water. Apply enough medicine to work up a lather and rub well into the scalp for 2 or 3 minutes, then rinse. Apply the medicine again and rinse thoroughly.

To use the soap form of salicylic acid:


  • Work up a lather with the soap, using hot water, and scrub the entire affected area with a washcloth or facial sponge or mitt.

  • If you are to use this soap in a foot bath, work up rich suds in hot water and soak the feet for 10 to 15 minutes. Then pat dry without rinsing.

To use the topical solution form of salicylic acid for acne:


  • Wet a cotton ball or pad with the topical solution and wipe the affected areas.

  • Do not rinse off medicine after treatment.

To use the topical solution form of salicylic acid for warts, corns, or calluses:


  • This medicine comes with patient instructions. Read them carefully before using.

  • This medicine is flammable. Do not use it near heat or open flame or while smoking.

  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.

  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.

  • Avoid breathing in the vapors from the medicine.

  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.

  • Apply the medicine one drop at a time to completely cover each wart, corn, or callus. Let dry.

  • For warts—Repeat one or two times a day as needed for up to 12 weeks, or as directed by your doctor, until wart is removed.

  • For corns and calluses—Repeat one or two times a day as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.

  • Corns and calluses may be soaked in warm water for 5 minutes to help in their removal.

  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

Unless your hands are being treated, wash them immediately after applying this medicine to remove any medicine that may be on them.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For cream dosage form:
    • For corns and calluses:
      • Adults and children—Use the 2 to 10% cream as needed. Use the 25 to 60% cream one time every three to five days.



  • For gel dosage form:
    • For acne:
      • Adults and children—Use the 0.5 to 5% gel one time a day.


    • For psoriasis:
      • Adults and children—Use the 5% gel one time a day.


    • For common warts:
      • Adults and children—Use the 5 to 26% gel one time a day.



  • For lotion dosage form:
    • For acne:
      • Adults and children—Use the 1 to 2% lotion one to three times a day.


    • For dandruff and antiseborrhic dermatitis of the scalp:
      • Adults and children—Use the 1.8 to 2% lotion on the scalp one or two times a day.



  • For ointment dosage form:
    • For acne:
      • Adults and children—Use the 3 to 6% ointment as needed.


    • For psoriasis and seborrheic dermatitis:
      • Adults and children—Use the 3 to 10% ointment as needed.


    • For common warts:
      • Adults and children—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every three to five days.



  • For pads dosage form:
    • For acne:
      • Adults and children—Use one to three times a day.



  • For plaster dosage form:
    • For corns, calluses, common warts, or plantar warts:
      • Adults and children—Use one time a day or one time every other day.



  • For shampoo dosage form:
    • For dandruff or seborrheic dermatitis of the scalp:
      • Adults and children—Use on the scalp one or two times a week.



  • For soap dosage form:
    • For acne:
      • Adults and children—Use as needed.



  • For topical solution dosage form:
    • For acne:
      • Adults and children—Use the 0.5 to 2% topical solution one to three times a day.


    • For common warts and plantar warts:
      • Adults and children—Use the 5 to 27% topical solution one or two times a day.


    • For corns and calluses:
      • Adults and children—Use the 12 to 27% topical solution one or two times a day.



Missed Dose


If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using Dr. Scholl's Clear Away One Step Plantar Wart Remover


When using salicylic acid, do not use any of the following preparations on the same affected area as this medicine, unless otherwise directed by your doctor:


  • Abrasive soaps or cleansers

  • Alcohol-containing preparations

  • Any other topical acne preparation or preparation containing a peeling agent (for example, benzoyl peroxide, resorcinol, sulfur, or tretinoin [vitamin A acid])

  • Cosmetics or soaps that dry the skin

  • Medicated cosmetics

  • Other topical medicine for the skin

To use any of the above preparations on the same affected area as salicylic acid may cause severe irritation of the skin.


Check with your doctor right away if you have nausea, vomiting, dizziness, loss of hearing, tinnitus, lethargy hyperpnea, diarrhea, and psychic disturbances. These could be symptoms of a serious condition called salicylate toxicity, especially in children under 12 years of age and patients with kidney or liver problems.


Dr. Scholl's Clear Away One Step Plantar Wart Remover Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


Less common or rare
  • Skin irritation not present before use of this medicine (moderate or severe)

Frequency not known
  • Dryness and peeling of skin

  • flushing

  • redness of skin

  • unusually warm skin

Symptoms of salicylic acid poisoning
  • Confusion

  • diarrhea

  • dizziness

  • fast or deep breathing

  • headache (severe or continuing)

  • hearing loss

  • lightheadedness

  • nausea

  • rapid breathing

  • ringing or buzzing in ears (continuing)

  • severe drowsiness

  • stomach pain

  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Skin irritation not present before use of this medicine (mild)

  • stinging

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical resources


  • Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical Side Effects (in more detail)
  • Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical Use in Pregnancy & Breastfeeding
  • Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical Drug Interactions
  • Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical Support Group
  • 1 Review for Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical - Add your own review/rating


Compare Dr. Scholl's Clear Away One Step Plantar Wart Remover Topical with other medications


  • Acne
  • Dermatological Disorders
  • Warts

Friday, 16 July 2010

Adorem




Adorem may be available in the countries listed below.


Ingredient matches for Adorem



Paracetamol

Paracetamol is reported as an ingredient of Adorem in the following countries:


  • Colombia

International Drug Name Search

Wednesday, 14 July 2010

Yuwan




Yuwan may be available in the countries listed below.


Ingredient matches for Yuwan



Sucralfate

Sucralfate is reported as an ingredient of Yuwan in the following countries:


  • Japan

International Drug Name Search

Tuesday, 6 July 2010

decitabine


Generic Name: decitabine (de SIT a been)

Brand Names: Dacogen


What is decitabine?

Decitabine is a cancer medication that interferes with the growth and spread of cancer cells in the body.


Decitabine is used to treat myelodysplastic syndromes (certain types of blood or bone marrow cancer).


Decitabine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about decitabine?


Before receiving this medication, tell your doctor if you have liver or kidney disease.


Do not use decitabine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. If a man fathers a child while using this medication, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment. Continue using condoms for at least 2 months after you stop receiving decitabine. You should not breast-feed while you are receiving decitabine.

Decitabine can lower blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding or injury. Your blood may need to be tested often. Visit your doctor regularly.


What should I discuss with my health care provider before receiving decitabine?


To make sure you can safely take decitabine, tell your doctor if you have any of these other conditions:



  • kidney disease; or




  • liver disease.




FDA pregnancy category D. Do not use decitabine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. If a man fathers a child while using this medication, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment. Continue using condoms for at least 2 months after you stop receiving decitabine. It is not known whether decitabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving decitabine.

How is decitabine given?


Decitabine is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Decitabine must be given slowly, and the IV infusion can take up to 3 hours to complete.


In most cases, a decitabine injection is given every 8 hours for 3 days. This 3-day treatment is usually repeated every 6 weeks. You will most likely receive at least 4 of these treatments.


You may be given other medications to prevent nausea or vomiting while you are receiving decitabine.


Decitabine can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.

What happens if I miss a dose?


Call your doctor for instructions if you miss an appointment for your decitabine injection.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include some of the serious side effects listed in this medication guide.


What should I avoid while receiving decitabine?


Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.


Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Decitabine side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • fever, chills, body aches, cough, sore throat, flu symptoms;




  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;




  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;




  • white patches or sores inside your mouth or on your lips; or




  • stabbing chest pain, wheezing, feeling short of breath, cough with yellow or green mucus;




  • swelling, pain, tenderness, or redness anywhere on your body; or




  • electrolyte imbalance (confusion, uneven heart rate, extreme thirst, increased urination, jerking muscle movements, leg discomfort, muscle weakness or limp feeling).



Less serious side effects may include:



  • headache, dizziness;




  • tired feeling;




  • nausea, vomiting, stomach pain, diarrhea, constipation;




  • cough;




  • increased thirst, increased urination, hunger, dry mouth, drowsiness;




  • joint pain; or




  • sleep problems (insomnia).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Decitabine Dosing Information


Usual Adult Dose for Myelodysplastic Syndrome:

Treatment Regimen - Option 1
First Treatment Cycle: 15 mg/m2 administered by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Patients may be premedicated with standard antiemetic therapy.

Subsequent Treatment Cycles: The above cycle should be repeated every 6 weeks. It is recommended that patients be treated for a minimum of 4 cycles; however, a complete or partial response may take longer than 4 cycles. Treatment may be continued as long as the patient continues to benefit.

If hematologic recovery (absolute neutrophil count (ANC) greater than or equal to 1000/microliter and platelets greater than or equal to 50,000/microliter) from a previous treatment cycle requires more than 6 weeks, then the next cycle of decitabine therapy should be delayed and dosing temporarily reduced by following this algorithm: Recovery requiring more than 6, but less than 8 weeks - decitabine dosing to be delayed for up to 2 weeks and the dose temporarily reduced to 11 mg/m2 every 8 hours (33 mg/m2/day, 99 mg/m2/cycle) upon restarting therapy. Recovery requiring more than 8, but less than 10 weeks - Patient should be assessed for disease progression (by bone marrow aspirates); in the absence of progression, the decitabine dose should be delayed up to 2 more weeks and the dose reduced to 11 mg/m2 every 8 hours (33 mg/m2/day, 99 mg/m2/cycle) upon restarting therapy, then maintained or increased in subsequent cycles as clinically indicated.

Treatment Regimen - Option 2
20 mg/m2 by continuous intravenous infusion over 1 hour repeated daily for 5 days. This cycle should be repeated every 4 weeks. Patients may be premedicated with standard antiemetic therapy.

If myelosuppression is present, subsequent treatment cycles of decitabine should be delayed until there is hematologic recovery (ANC greater than or equal to 1,000/mcL platelets greater than or equal to 50,000/mcL ).


What other drugs will affect decitabine?


There may be other drugs that can interact with decitabine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More decitabine resources


  • Decitabine Side Effects (in more detail)
  • Decitabine Dosage
  • Decitabine Use in Pregnancy & Breastfeeding
  • Decitabine Drug Interactions
  • Decitabine Support Group
  • 0 Reviews for Decitabine - Add your own review/rating


  • decitabine Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information

  • Decitabine Professional Patient Advice (Wolters Kluwer)

  • Decitabine MedFacts Consumer Leaflet (Wolters Kluwer)

  • Decitabine Monograph (AHFS DI)

  • Dacogen Prescribing Information (FDA)

  • Dacogen Consumer Overview



Compare decitabine with other medications


  • Acute Myeloid Leukemia
  • Myelodysplastic Syndrome


Where can I get more information?


  • Your doctor or pharmacist can provide more information about decitabine.

See also: decitabine side effects (in more detail)


Monday, 5 July 2010

Gestakadin




Gestakadin may be available in the countries listed below.


Ingredient matches for Gestakadin



Norethisterone

Norethisterone 17ß-acetate (a derivative of Norethisterone) is reported as an ingredient of Gestakadin in the following countries:


  • Germany

International Drug Name Search

Saturday, 3 July 2010

Cholestyramine




In the US, Cholestyramine (cholestyramine systemic) is a member of the drug class bile acid sequestrants and is used to treat Crohn's Disease, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa - Elevated LDL, Hyperlipoproteinemia Type IIb - Elevated LDL VLDL, Irritable Bowel Syndrome and Pruritus of Partial Biliary Obstruction.

US matches:

  • Cholestyramine Powder

  • Cholestyramine Light

  • Cholestyramine

  • Cholestyramine Resin

Ingredient matches for Cholestyramine



Colestyramine

Cholestyramine (BAN) is also known as Colestyramine (Rec.INN)

International Drug Name Search

Glossary

BANBritish Approved Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.