Clonalgin may be available in the countries listed below.
Clonixin lysine salt (a derivative of Clonixin) is reported as an ingredient of Clonalgin in the following countries:
International Drug Name Search
Ph. Eur.
0008001-22-7
Nutrient
International Drug Name Search
Glossary
| IS | Inofficial Synonym |
| JAN | Japanese Accepted Name |
| OS | Official Synonym |
| PH | Pharmacopoeia Name |
| Ph. Eur. | European Pharmacopoeia |
or-FEN-a-dreen SIT-rate, AS-pir-in, KAF-een
In the U.S.
Available Dosage Forms:
Therapeutic Class: Skeletal Muscle Relaxant, Centrally Acting/Salicylate, Aspirin Combination
Pharmacologic Class: Orphenadrine
Chemical Class: Salicylate, Aspirin
Orphenadrine and aspirin combination is used to help relax certain muscles in your body and relieve the pain and discomfort caused by strains, sprains, or other injury to your muscles. However, orphenadrine, aspirin, and caffeine does not take the place of rest, exercise, or other treatment that your doctor may recommend for your medical problem.
Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects. Actions in the CNS may also be responsible for some of its side effects. Orphenadrine also has other actions (antimuscarinic) that may be responsible for some of its side effects.
This combination medicine also contains caffeine.
In the U.S., this combination medicine is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For orphenadrine, aspirin, and caffeine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to orphenadrine, aspirin, and caffeine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Do not give a medicine containing aspirin to a child or a teenager with a fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's doctor. This is very important because aspirin may cause a serious illness called Reye's syndrome in children with fever caused by a virus infection, especially flu or chickenpox. Children who do not have a virus infection may also be more sensitive to the effects of aspirin, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. This may increase the chance of side effects during treatment.
There is no specific information about the use of orphenadrine in children.
Elderly people are especially sensitive to the effects of aspirin. This may increase the chance of side effects during treatment.
There is no specific information about the use of orphenadrine in the elderly.
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | D | Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. |
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking orphenadrine, aspirin, and caffeine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using orphenadrine, aspirin, and caffeine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using orphenadrine, aspirin, and caffeine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using orphenadrine, aspirin, and caffeine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using orphenadrine, aspirin, and caffeine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use orphenadrine, aspirin, and caffeine, or give you special instructions about the use of food, alcohol, or tobacco.
The presence of other medical problems may affect the use of orphenadrine, aspirin, and caffeine. Make sure you tell your doctor if you have any other medical problems, especially:
Take orphenadrine, aspirin, and caffeine with food or a full glass (8 ounces) of water to lessen stomach irritation.
Do not take orphenadrine, aspirin, and caffeine if it has a strong vinegar-like odor. This odor means the aspirin in it is breaking down. If you have any questions about this, check with your health care professional.
Do not take more of orphenadrine, aspirin, and caffeine than your doctor ordered to lessen the chance of side effects or overdose.
The dose of orphenadrine, aspirin, and caffeine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of orphenadrine, aspirin, and caffeine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of orphenadrine, aspirin, and caffeine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
If you will be taking orphenadrine, aspirin, and caffeine for a long time (for example, more than a few weeks), your doctor should check your progress at regular visits.
Check the labels of all nonprescription (over-the-counter [OTC]) and prescription medicines you now take. If any contain orphenadrine or aspirin or other salicylates be especially careful, since taking them while taking orphenadrine, aspirin, and caffeine may lead to overdose. If you have any questions about this, check with your health care professional.
Too much use of acetaminophen or certain other medicines together with the aspirin in this combination medicine may increase the chance of unwanted effects. The risk depends on how much of each medicine you take every day, and on how long you take the medicines together. If your doctor directs you to take these medicines together on a regular basis, follow his or her directions carefully. However, do not take acetaminophen or any of the following medicines together with this combination medicine for more than a few days, unless your doctor has directed you to do so and is following your progress:
For diabetic patients:
Do not take orphenadrine, aspirin, and caffeine for 5 days before any surgery, including dental surgery, unless otherwise directed by your medical doctor or dentist. Taking aspirin during this time may cause bleeding problems.
The orphenadrine in this combination medicine may add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; other muscle relaxants; or anesthetics, including some dental anesthetics. Also, stomach problems may be more likely to occur if you drink alcoholic beverages while you are taking aspirin. Do not drink alcoholic beverages, and check with your doctor before taking any of the medicines listed above, while you are using orphenadrine, aspirin, and caffeine.
orphenadrine, aspirin, and caffeine may cause some people to have blurred vision or to become drowsy, dizzy, lightheaded, faint, or less alert than they are normally. Make sure you know how you react to orphenadrine, aspirin, and caffeine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.
Dryness of the mouth may occur while you are taking orphenadrine, aspirin, and caffeine. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.
If you think that you or someone else may have taken an overdose of orphenadrine, aspirin, and caffeine, get emergency help at once. Taking an overdose of orphenadrine, aspirin, and caffeine may cause unconsciousness or death. Signs of overdose include convulsions (seizures), hearing loss, confusion, ringing or buzzing in the ears, severe drowsiness or tiredness, severe excitement or nervousness, and fast or deep breathing.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Get emergency help immediately if any of the following symptoms of overdose occur:
Check with your doctor as soon as possible if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Acromax may be available in the countries listed below.
Cromoglicic Acid disodium salt (a derivative of Cromoglicic Acid) is reported as an ingredient of Acromax in the following countries:
International Drug Name Search
UK matches:
Vancomycin Hydrochloride (BANM) is known as Vancomycin in the US.
International Drug Name Search
Glossary
| BANM | British Approved Name (Modified) |
| SPC | Summary of Product Characteristics (UK) |
Migracin may be available in the countries listed below.
Amikacin sulfate (a derivative of Amikacin) is reported as an ingredient of Migracin in the following countries:
International Drug Name Search
Medifen may be available in the countries listed below.
Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Medifen in the following countries:
International Drug Name Search
Tilazem may be available in the countries listed below.
Diltiazem hydrochloride (a derivative of Diltiazem) is reported as an ingredient of Tilazem in the following countries:
International Drug Name Search
Singloben may be available in the countries listed below.
Glipizide is reported as an ingredient of Singloben in the following countries:
International Drug Name Search
Beta K may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Potassium Chloride is reported as an ingredient of Beta K in the following countries:
International Drug Name Search
In the US, Fluxid (famotidine systemic) is a member of the drug class H2 antagonists and is used to treat Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Erosive Esophagitis, GERD, Indigestion, Pathological Hypersecretory Conditions, Peptic Ulcer, Stomach Ulcer, Upper GI Hemorrhage, Urticaria and Zollinger-Ellison Syndrome.
US matches:
Famotidine is reported as an ingredient of Fluxid in the following countries:
International Drug Name Search
Amicar is a brand name of aminocaproic acid, approved by the FDA in the following formulation(s):
Yes. The following products are equivalent to Amicar:
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Amicar. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: About generic drugs.
There are no current U.S. patents associated with Amicar.
